rs359895
This is a regulatory region variant variant in the ZNF804A gene.
▶Research that mentions this SNP (1)
▶A comprehensive meta‐analysis of ZNF804A SNPs in the risk of schizophrenia among Asian populationsMeta-analysisN=31,278Liang Huang et al.(2016)· American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
Meta-analysis of ZNF804A SNPs in 13,452 schizophrenia cases and 17,826 controls from Asian populations found that rs1344706 was nominally associated with schizophrenia (P=4.26×10⁻², OR=1.048) and rs1366842 showed significant association (P=9.96×10⁻³, OR=1.095). These associations were strengthened when bipolar disorder samples were included (rs1344706: P=1.85×10⁻², OR=1.057), suggesting ZNF804A variants confer small but detectable risk for schizophrenia and related psychotic disorders in Asian populations.
About ZNF804A
The protein encoded by this gene is a zinc finger binding protein. Polymorphisms in this gene, especially rs1344706, are thought to confer increased susceptibility to schizophrenia, bipolar disorder, and heroin addiciton. [provided by RefSeq, Nov 2015]
View all ZNF804A variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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