rs368187
This is a coding sequence variant variant in the LOC105370452 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
thyroid carcinoma
Gudmundsson J et al. “A genome-wide association study yields five novel thyroid cancer risk loci.” Nature Communications 8:14517 (2017)
Allele G
OR 1.39
p 5.0e-23
N 290,551
Large GWAS
European
goiter
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele C
OR 0.20
p 2.0e-17
N 633,436
Large GWAS
multi-ancestry
differentiated thyroid carcinoma
Truong T et al. “Multiethnic genome-wide association study of differentiated thyroid cancer in the EPITHYR consortium.” International Journal of Cancer 148(12):2935-2946 (2021)
Allele G
OR 1.47
p 4.0e-13
N 3,527
Major Consortium StudyLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…