rs368484670

This variant is located in the NMRAL1 gene.

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ClinVar annotation

Uncertain Significance★☆☆☆

1 submitter

not specified

About NMRAL1

This gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF-kappaB in a ubiquitylation-dependent manner. It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3-mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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