rs370235958

This variant is located in the LRRK1 gene.

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ClinVar annotation

Uncertain Significance★★★☆
3 submitters2 publications

not provided; LRRK1-related disorder; Inborn genetic diseases

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About LRRK1

This gene encodes a multi-domain protein that is a leucine-rich repeat kinase and a GDP/GTP binding protein. The encoded protein is thought to play a role in the regulation of bone mass. Mice lacking a similar gene showed severe osteopetrosis, increased bone mineralization and decreased bone resorption. [provided by RefSeq, Jan 2017]

View all LRRK1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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