rs372229746
This variant is located in the RASA4B gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
circadian rhythm
Jones SE et al. “Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci.” Plos Genetics 12(8):e1006125 (2016)
Allele G
OR 0.03
p 8.0e-15
N 127,898
Large GWAS
European
Lane JM et al. “Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank.” Nature Communications 7:10889 (2016)
Allele G
OR 0.03
p 5.0e-10
N 100,420
Major Consortium StudyLarge GWAS
European
About RASA4B
Predicted to enable GTPase activator activity; phospholipid binding activity; and zinc ion binding activity. Predicted to be involved in cellular response to calcium ion; intracellular signal transduction; and negative regulation of Ras protein signal transduction. Predicted to be located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all RASA4B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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