rs372605131
This variant is located in the TRIM49 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
response to steroid, systemic lupus erythematosus, idiopathic osteonecrosis of the femoral head
Suetsugu H et al. “Novel susceptibility loci for steroid-associated osteonecrosis of the femoral head in systemic lupus erythematosus.” Human Molecular Genetics 31(7):1082-1095 (2022)
Allele C
OR 1.78
p 1.0e-8
N 96,224
Large GWAS
East Asian
About TRIM49
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This gene has been found to be preferentially expressed in testis. Related pseudogenes and gene duplicates have also been identified on chromosome 11. [provided by RefSeq, Aug 2010]
View all TRIM49 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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