rs3739998
This is a protein-altering variant in the JCAD gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
coronary artery disease
Erdmann J et al. “Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23.” European Heart Journal 32(2):158-68 (2011)
Allele C
OR 1.15
p 1.0e-11
N 2,905
Large GWAS
European
About JCAD
This gene encodes an endothelial cell-to-cell junction protein. Naturally occurring mutations in this gene are associated with coronary artery disease, late onset alzheimer disease, and emphysema distribution. [provided by RefSeq, Mar 2017]
View all JCAD variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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