rs374533080
This variant is located in the ARHGAP42 gene.
▶ClinVar annotation
About ARHGAP42
This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension. [provided by RefSeq, Jul 2017]
View all ARHGAP42 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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