rs3749833

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

asthma

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele C

OR 0.08

p 1.0e-27

N 394,626

Large GWAS

European

Olafsdottir TA et al. “Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis.” Nature Communications 11(1):393 (2020)

Allele C

OR 1.08

p 1.0e-26

N 771,388

Large GWAS

European

Ferreira MAR et al. “Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.” American Journal of Human Genetics 104(4):665-684 (2019)

Allele C

OR 1.08

p 3.0e-26

N 341,215

Large GWAS

European

Shrine N et al. “Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.” The Lancet. Respiratory Medicine 7(1):20-34 (2019)

Allele C

OR 1.14

p 6.0e-14

N 30,810

Large GWAS

European

asthma, chronic obstructive pulmonary disease

John C et al. “Genetic Associations and Architecture of Asthma-COPD Overlap.” Chest 161(5):1155-1166 (2022)

Allele C

OR 1.12

p 9.0e-12

N 48,428

Large GWAS

multi-ancestry

allergic disease

Ferreira MA et al. “Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.” Nature Genetics 49(12):1752-1757 (2017)

Allele C

OR 1.04

p 3.0e-11

N 360,838

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

rs3749833

GWAS Catalog Trait Associations (3)

asthma

asthma, chronic obstructive pulmonary disease

allergic disease

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