rs375066

This variant is located in the ZNF45 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

breast carcinoma

Michailidou K et al. “Association analysis identifies 65 new breast cancer risk loci.” Nature 551(7678):92-94 (2017)

Allele C

OR 0.05

p 2.0e-14

N 139,274

Large GWAS

multi-ancestry

About ZNF45

Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of DNA-templated transcription. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all ZNF45 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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