rs3761445

▶

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

triglyceride measurement, body fat percentage

Huang LO et al. “Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities.” Nature Metabolism 3(2):228-243 (2021)

Allele G

OR —

p 5.0e-18

N 278,577

Large GWAS

multi-ancestry

triglyceride measurement

Spracklen CN et al. “Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.” Human Molecular Genetics 26(9):1770-1784 (2017)

Allele A

OR 0.02

p 3.0e-12

N 206,044

Large GWAS

multi-ancestry

body fat percentage, high density lipoprotein cholesterol measurement

Huang LO et al. “Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities.” Nature Metabolism 3(2):228-243 (2021)

Allele G

OR —

p 2.0e-11

N 287,833

Large GWAS

multi-ancestry

body fat percentage

Lu Y et al. “New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.” Nature Communications 7:10495 (2016)

Allele G

OR 0.04

p 3.0e-9

N 78,525

Large GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…