rs376522516

This variant is located in the IPCEF1 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

tympanic membrane perforation

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 3.66
p 3.0e-11
N 629,858
Major Consortium StudyLarge GWAS
multi-ancestry

About IPCEF1

Predicted to enable peroxidase activity. Predicted to be involved in response to oxidative stress. Predicted to be located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all IPCEF1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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