rs377505014

This variant is located in the STK33 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

alcohol consumption quality

Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)

Allele A

OR 0.01

p 2.0e-14

N 2,965,643

Large GWAS

European, East Asian, Hispanic or Latin American, African unspecified

About STK33

Enables protein serine/threonine kinase activity. Involved in spermatogenesis. Predicted to be located in manchette. Predicted to be active in nucleus. Implicated in colorectal cancer; depressive disorder; and spermatogenic failure 93. [provided by Alliance of Genome Resources, Jul 2025]

View all STK33 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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