rs3784155
This is a intron variant variant in the SYNJ2BP gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
cholesterol:total lipids ratio, cholesteryl esters:total lipids ratio
Karjalainen MK et al. “Genome-wide characterization of circulating metabolic biomarkers.” Nature 628(8006):130-138 (2024)
Allele A
OR 0.04
p 3.0e-11
N 136,016
Large GWAS
multi-ancestry
About SYNJ2BP
Predicted to enable type II activin receptor binding activity. Involved in several processes, including negative regulation of endothelial cell migration; negative regulation of sprouting angiogenesis; and regulation of signal transduction. Located in mitochondrial outer membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all SYNJ2BP variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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