rs3797677

This variant is located in the MAN2A1 gene.

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ClinVar annotation

Benign★☆☆☆
2 submitters1 publication

not provided; Familial pancreatic carcinoma; Hepatocellular carcinoma; Cervical cancer

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About MAN2A1

This gene encodes a glycosyl hydrolase that localizes to the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus. [provided by RefSeq, Dec 2013]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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