rs3809060

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Inguinal hernia

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)

Allele G

OR 0.11

p 6.0e-36

N 618,450

Major Consortium StudyLarge GWAS

multi-ancestry

Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)

Allele G

OR 0.13

p 1.0e-27

N 623,807

Large GWAS

multi-ancestry

Wei J et al. “Identification of fifty-seven novel loci for abdominal wall hernia development and their biological and clinical implications: results from the UK Biobank.” Hernia : the Journal of Hernias and Abdominal Wall Surgery 26(1):335-348 (2022)

Allele G

OR 1.12

p 1.0e-22

N 275,546

Major Consortium StudyLarge GWAS

European

Jorgenson E et al. “A genome-wide association study identifies four novel susceptibility loci underlying inguinal hernia.” Nature Communications 6:10130 (2015)

Allele G

OR 1.11

p 4.0e-14

N 72,805

Large GWAS

European

visceral:abdominal adipose tissue ratio measurement

Agrawal S et al. “Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots.” Nature Communications 13(1):3771 (2022)

Allele G

OR 0.06

p 6.0e-9

N 19,981

Large GWAS

European, East Asian, South Asian, African unspecified, NR

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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