rs3817928

This is a regulatory region variant variant in the ADGRG6 gene.

▶

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

FEV/FVC ratio, pulmonary function measurement

Hancock DB et al. “Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.” Nature Genetics 42(1):45-52 (2010)

Allele A

OR 0.42

p 1.0e-9

N 20,890

Large GWAS

European

About ADGRG6

This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009]

View all ADGRG6 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Loading comments…