rs3853445
This is a regulatory region variant variant.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
atrial fibrillation
Roselli C et al. “Multi-ethnic genome-wide association study for atrial fibrillation.” Nature Genetics 50(9):1225-1233 (2018)
Allele T
OR 1.22
p 6.0e-113
N 588,190
Large GWAS
multi-ancestry
Nielsen JB et al. “Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.” Nature Genetics 50(9):1234-1239 (2018)
Allele T
OR 1.16
p 4.0e-52
N 1,030,836
Large GWAS
European
Low SK et al. “Identification of six new genetic loci associated with atrial fibrillation in the Japanese population.” Nature Genetics 49(6):953-958 (2017)
Allele T
OR 1.33
p 2.0e-34
N 36,792
Large GWAS
multi-ancestry
cardiac arrhythmia
Ishigaki K et al. “Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.” Nature Genetics 52(7):669-679 (2020)
Allele C
OR 0.85
p 3.0e-41
N 212,453
Large GWAS
East Asian
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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