rs3865188

This is a intergenic variant variant.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body mass index

Huang J et al. “Genomics and phenomics of body mass index reveals a complex disease network.” Nature Communications 13(1):7973 (2022)
Allele T
OR 0.01
p 9.0e-11
N 1,122,049
Large GWAS
European
Sidorenko J et al. “Genetic architecture reconciles linkage and association studies of complex traits.” Nature Genetics 56(11):2352-2360 (2024)
Allele T
OR 0.01
p 2.0e-9
N 650,000
Large GWAS
European
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Research that mentions this SNP (1)

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CDH13 gene coding t-cadherin influences variations in plasma adiponectin levels in the Japanese population
AssociationN=684Hiroko Morisaki et al.(2012)· Human Mutation

This Chinese family-based sib-pair study of 342 discordant pairs (684 individuals) examined CDH13 genetic polymorphisms and their association with adiponectin levels and ischemic stroke risk. CDH13 rs7193788 was significantly associated with ischemic stroke (OR=1.55, 95% CI: 1.07-2.24, P=0.020), and both rs4783244 and rs7193788 were associated with reduced adiponectin levels. A significant interaction was found between rs7193788 and diabetes, with diabetic patients carrying risk genotypes showing substantially elevated stroke risk (OR=2.64, 95% CI: 1.58-4.40).

Traits studied:Adiponectin levelsHigh-molecular weight adiponectinIschemic stroke
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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