rs3890011

This is a intron variant variant in the CYP4A11 gene.

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Research that mentions this SNP (1)

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Genome‐wide interaction study of single‐nucleotide polymorphisms and alcohol consumption on blood pressure: The Ansan and Ansung study of the Korean Genome and Epidemiology Study (KoGES)
ReviewYoungjun Kim et al.(2020)· Genetic Epidemiology

This is a comprehensive review of gene-environment interactions in hypertension, summarizing recent research on how genetic variants interact with lifestyle factors (diet, alcohol, smoking, obesity, physical activity) to influence blood pressure regulation. The paper discusses key genetic variants including GNB3-C825T, BCL11B-rs8022678, NOS3-rs1799983, CYP4A11 variants, and FTO-rs9930333, and recommends lifestyle modifications and selective genetic testing for hypertension management in community healthcare settings.

Traits studied:Blood pressureDiastolic pressureHypertensionMetabolic syndromeSalt sensitivitySystolic pressure
PubMedDOIMetascience Observatory

About CYP4A11

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jan 2016]

View all CYP4A11 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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