rs3893464
This is a regulatory region variant variant.
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
eosinophil count
Astle WJ et al. “The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.” Cell 167(5):1415-1429.e19 (2016)
Allele A
OR 0.06
p 8.0e-55
N 172,275
Large GWAS
European
basophil count, eosinophil count
Astle WJ et al. “The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.” Cell 167(5):1415-1429.e19 (2016)
Allele A
OR 0.06
p 7.0e-54
N 171,771
Large GWAS
European
monocyte count
Kachuri L et al. “Genetic determinants of blood-cell traits influence susceptibility to childhood acute lymphoblastic leukemia.” American Journal of Human Genetics 108(10):1823-1835 (2021)
Allele G
OR —
p 7.0e-43
N 234,690
Large GWAS
European
Graves disease
Nakabayashi K et al. “Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.” Journal of Human Genetics 56(11):772-8 (2011)
Allele G
OR 1.53
p 2.0e-20
N 3,837
Large GWAS
East Asian
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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