rs389883

This is a regulatory region variant variant in the STK19 gene.

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GWAS Catalog Trait Associations (5)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

fatty acid amount

Sun Y et al. “GWAS and multi-omics integrative analysis reveal novel loci and their molecular mechanisms for circulating fatty acids.” Hgg Advances 6(4):100470 (2025)

Allele G

OR —

p 8.0e-25

N 128,922

Large GWAS

European

omega-6 polyunsaturated fatty acid measurement

Sun Y et al. “GWAS and multi-omics integrative analysis reveal novel loci and their molecular mechanisms for circulating fatty acids.” Hgg Advances 6(4):100470 (2025)

Allele G

OR —

p 7.0e-24

N 128,922

Large GWAS

European

schizophrenia, major depressive disorder

Amare AT et al. “Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression.” Molecular Psychiatry 25(7):1420-1429 (2020)

Allele T

OR —

p 1.0e-12

N 220,081

Large GWAS

European

polyunsaturated fatty acid measurement

Sun Y et al. “GWAS and multi-omics integrative analysis reveal novel loci and their molecular mechanisms for circulating fatty acids.” Hgg Advances 6(4):100470 (2025)

Allele G

OR —

p 4.0e-8

N 128,922

Large GWAS

European

saturated fatty acids measurement

Sun Y et al. “GWAS and multi-omics integrative analysis reveal novel loci and their molecular mechanisms for circulating fatty acids.” Hgg Advances 6(4):100470 (2025)

Allele G

OR —

p 8.0e-22

N 128,922

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

rs389883

GWAS Catalog Trait Associations (5)

fatty acid amount

omega-6 polyunsaturated fatty acid measurement

schizophrenia, major depressive disorder

polyunsaturated fatty acid measurement

saturated fatty acids measurement

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