rs3914502
This variant is located in the NAALADL2 gene.
▶Research that mentions this SNP (1)
▶No association between a common single nucleotide polymorphism, rs4141463, in the MACROD2 gene and autism spectrum disorderAssociationN=2,192Sarah Curran et al.(2011)· American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
A two-stage genome-wide association study (GWAS) of 315 autism spectrum disorder (ASD) cases and 1,115 controls in the Taiwanese Han population identified 7 SNPs with suggestive associations (p = 3.4-9.9 × 10⁻⁶), including variants in OR2M4 (rs10888329, rs6672981, rs4642918, rs4397683; OR = 0.55-0.56), STYK1 (rs16922945; OR = 1.86), and MNT (rs2447097, rs2447095; OR = 1.52-1.53). Fine-mapping identified associations in GLIS1 (rs12082358, rs12080993), NAALADL2 (rs3914502, rs2222447), and the GLIPR1/KRR1 region. Pathway analysis revealed olfactory and G protein-coupled receptor signaling as important for ASD etiology.
About NAALADL2
Predicted to act upstream of or within response to bacterium. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
View all NAALADL2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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