rs393152

This is a downstream gene variant variant in the LINC02210 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Parkinson disease

Simón-Sánchez J et al. “Genome-wide association study reveals genetic risk underlying Parkinson's disease.” Nature Genetics 41(12):1308-12 (2009)
Allele A
OR 1.30
p 2.0e-16
N 5,691
Large GWAS
European
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Research that mentions this SNP (1)

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Genomewide association study for susceptibility genes contributing to familial Parkinson disease
AssociationN=1,724Nathan Pankratz et al.(2009)· Human Genetics

First genome-wide association study (GWAS) of familial Parkinson disease in 857 cases and 867 controls identified association with SNPs in GAK/DGKQ (p=3.4×10⁻⁶, OR=1.69), SNCA (p=5.5×10⁻⁵, OR=1.35), and MAPT (p=2.0×10⁻⁵, OR=0.56). Meta-analysis with Fung et al. strengthened evidence for GAK/DGKQ (p=2.5×10⁻⁷) and MAPT regions, confirming previously implicated genes and nominating new susceptibility loci for PD.

Traits studied:Parkinson diseasefamilial Parkinson disease
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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