rs404256
This is a upstream gene variant variant in the BACH2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
serum IgG glycosylation measurement
Lauc G et al. “Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.” Plos Genetics 9(1):e1003225 (2013)
Allele C
OR 0.21
p 7.0e-9
N 2,247
Large GWAS
European
About BACH2
Enables sequence-specific double-stranded DNA binding activity. Involved in primary adaptive immune response involving T cells and B cells. Located in cytosol and nucleoplasm. Part of RNA polymerase II transcription regulator complex. Implicated in immunodeficiency 60. [provided by Alliance of Genome Resources, Jul 2025]
View all BACH2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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