rs409763

This variant is located in the FCGR2A gene.

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ClinVar annotation

Uncertain Significance★★★☆
3 submitters1 publication

Malaria, susceptibility to;Cystic fibrosis;Systemic lupus erythematosus; not provided; Familial pancreatic carcinoma; Colon adenocarcinoma; Malignant tumor of esophagus; Nonpapillary renal cell carcinoma; Cervical cancer; Familial cancer of breast; Clear cell carcinoma of kidney

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About FCGR2A

This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]

View all FCGR2A variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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