rs41267397

This variant is located in the BCAN gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

brevican core protein measurement

Sun BB et al. “Genomic atlas of the human plasma proteome.” Nature 558(7708):73-79 (2018)

Allele T

OR —

β 2.020

p 2.0e-26

N 3,301

Large GWAS

European

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ClinVar annotation

Likely Benign★☆☆☆

1 submitter1 publication

View on ClinVar →

About BCAN

This gene encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. This protein is developmentally regulated and may function in the formation of the brain extracellular matrix. This protein is highly expressed in gliomas and may promote the growth and cell motility of brain tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

View all BCAN variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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