rs41298997
This is a intron variant variant in the IKBKE gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
psoriasis
Tsoi LC et al. “Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants.” Nature Communications 8:15382 (2017)
Allele T
OR 1.13
p 2.0e-8
N 287,323
Meta-analysisLarge GWAS
European
About IKBKE
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009]
View all IKBKE variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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