rs413778

This is a downstream gene variant variant in the LINC02210 gene.

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Research that mentions this SNP (1)

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Independent Replication of an Association of CNVR7113.6 with Crohnʼs Disease in Caucasians

AssociationN=5,640Rebecca L. Roberts et al.(2012)· Inflammatory Bowel Diseases

This replication study confirms the association of copy number variant CNVR7113.6 on chromosome 17q21.31 with Crohn's disease susceptibility. The minor C allele of tagging SNP rs413778 conferred significant protection against CD (meta-analysis OR=0.86, 95% CI 0.80-0.92, P=1.19E-05) when combining New Zealand and Spanish cohorts (1,200 CD patients) with imputed data from WTCCC and NIDDK. No association was detected with ulcerative colitis, suggesting CD-specific disease modification.

Traits studied:Crohn's diseaseInflammatory bowel diseaseUlcerative colitis

PubMed DOI Metascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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