rs42202

▶

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Hiatus hernia

Ahmed WU et al. “Shared genetic architecture of hernias: A genome-wide association study with multivariable meta-analysis of multiple hernia phenotypes.” Plos One 17(12):e0272261 (2022)

Allele A

OR 1.14

p 8.0e-16

N 193,788

Meta-analysisLarge GWAS

European

diaphragmatic hernia

Campbell M et al. “Identification of 14 novel susceptibility loci for diaphragmatic hernia development and their biological and clinical implications: results from the UK Biobank.” Surgical Endoscopy 36(10):7647-7651 (2022)

Allele A

OR —

p 3.0e-10

N 275,546

Major Consortium StudyLarge GWAS

Barrett's esophagus

Schröder J et al. “GWAS meta-analysis of 16 790 patients with Barrett's oesophagus and oesophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level.” Gut 72(4):612-623 (2023)

Allele A

OR 0.19

p 9.0e-9

N 43,684

Meta-analysisLarge GWAS

European

Hernia

Ahmed WU et al. “Shared genetic architecture of hernias: A genome-wide association study with multivariable meta-analysis of multiple hernia phenotypes.” Plos One 17(12):e0272261 (2022)

Allele A

OR 1.08

p 2.0e-11

N 375,822

Meta-analysisLarge GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…