rs4236709
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
level of alkaline phosphatase, placental type in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.05
p 1.0e-18
N 47,745
Large GWAS
European
lung adenocarcinoma
Qin N et al. “Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma.” Frontiers of Medicine 15(2):275-291 (2021)
Allele G
OR 0.85
p 9.0e-17
N 42,936
Large GWAS
East Asian, European
Gorman BR et al. “Multi-ancestry GWAS meta-analyses of lung cancer reveal susceptibility loci and elucidate smoking-independent genetic risk.” Nature Communications 15(1):8629 (2024)
Allele G
OR 1.12
p 4.0e-13
N 80,888
Large GWAS
European
McKay JD et al. “Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.” Nature Genetics 49(7):1126-1132 (2017)
Allele G
OR 1.13
p 1.0e-10
N 66,756
Large GWAS
European
Dai J et al. “Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.” The Lancet. Respiratory Medicine 7(10):881-891 (2019)
Allele G
OR 1.20
p 1.0e-10
N 42,936
Large GWAS
multi-ancestry
glomerular filtration rate
Hughes O et al. “Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas.” Cell Genomics 4(1):100468 (2024)
Allele G
OR 7.54
p 5.0e-14
N 145,732
Large GWAS
multi-ancestry
non-small cell lung carcinoma
Qin N et al. “Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma.” Frontiers of Medicine 15(2):275-291 (2021)
Allele G
OR 0.89
p 1.0e-12
N 54,475
Large GWAS
multi-ancestry
Dai J et al. “Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.” The Lancet. Respiratory Medicine 7(10):881-891 (2019)
Allele G
OR 1.17
p 1.0e-9
N 54,475
Large GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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