rs4243085
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
glomerular filtration rate
Liu H et al. “Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease.” Nature Genetics 54(7):950-962 (2022)
Allele C
OR 7.33
p 2.0e-13
N 1,508,659
Large GWAS
multi-ancestry
cardiovascular disease biomarker measurement
Gummesson A et al. “A genome-wide association study of imaging-defined atherosclerosis.” Nature Communications 16(1):2266 (2025)
Allele C
OR 0.14
p 5.0e-11
N 24,811
Large GWAS
European
coronary artery calcification
Gummesson A et al. “A genome-wide association study of imaging-defined atherosclerosis.” Nature Communications 16(1):2266 (2025)
Allele C
OR 0.05
p 3.0e-10
N 26,000
Large GWAS
European
BMI-adjusted waist-hip ratio
Pulit SL et al. “Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.” Human Molecular Genetics 28(1):166-174 (2019)
Allele C
OR 0.01
p 1.0e-8
N 379,501
Meta-analysisLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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