rs4244811
This variant is located in the LTBP3 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
stenosing tenosynovitis
Patel B et al. “Shared genetic susceptibility between trigger finger and carpal tunnel syndrome: a genome-wide association study.” The Lancet. Rheumatology 4(8):e556-e565 (2022)
Allele G
OR 6.29
p 3.0e-10
N 439,487
Large GWAS
European
▶ClinVar annotation
Benign★★★☆
2 submitters1 publicationAbout LTBP3
The protein encoded by this gene forms a complex with transforming growth factor beta (TGF-beta) proteins and may be involved in their subcellular localization. Activation of this complex requires removal of the encoded binding protein. This protein also may play a structural role in the extracellular matrix. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]
View all LTBP3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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