rs4247364

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

atopic eczema

Budu-Aggrey A et al. “European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.” Nature Communications 14(1):6172 (2023)

Allele C

OR 0.97

p 2.0e-17

N 864,982

Meta-analysisLarge GWAS

European

asthma

Han Y et al. “Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma.” Nature Communications 11(1):1776 (2020)

Allele G

OR 1.05

p 9.0e-14

N 303,859

Large GWAS

European

Olafsdottir TA et al. “Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis.” Nature Communications 11(1):393 (2020)

Allele G

OR 1.04

p 2.0e-10

N 771,388

Large GWAS

European

Valette K et al. “Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank.” Communications Biology 4(1):700 (2021)

Allele G

OR 0.05

p 2.0e-10

N 408,422

Major Consortium StudyLarge GWAS

European

Zhu Z et al. “Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.” The European Respiratory Journal 54(6) (2019)

Allele G

OR 1.05

p 8.0e-12

N 394,283

Large GWAS

multi-ancestry

Johansson Å et al. “Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema.” Human Molecular Genetics 28(23):4022-4041 (2019)

Allele G

OR —

p 2.0e-11

N 281,699

Major Consortium StudyLarge GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

rs4247364

GWAS Catalog Trait Associations (2)

atopic eczema

asthma

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