rs4318109

This is a downstream gene variant variant in the DGKH gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

insulin measurement

Meeks KAC et al. “Genome-wide analyses of multiple obesity-related cytokines and hormones informs biology of cardiometabolic traits.” Genome Medicine 13(1):156 (2021)

Allele A

OR 1.30

p 3.0e-9

N 974

Small GWAS

multi-ancestry

About DGKH

This gene encodes a member of the diacylglycerol kinase (DGK) enzyme family. Members of this family are involved in regulating intracellular concentrations of diacylglycerol and phosphatidic acid. Variation in this gene has been associated with bipolar disorder. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Jul 2014]

View all DGKH variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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