rs441810

This is a regulatory region variant variant in the FAM3B gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

level of carcinoembryonic antigen-related cell adhesion molecule 5 in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele G

OR 0.09

p 1.0e-49

N 47,745

Large GWAS

European

cancer biomarker measurement

He M et al. “A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.” Gut 63(1):143-51 (2014)

Allele G

OR 0.07

p 3.0e-22

N 3,451

Large GWAS

East Asian

About FAM3B

Predicted to enable cytokine activity. Involved in insulin secretion. Located in extracellular exosome. [provided by Alliance of Genome Resources, Jul 2025]

View all FAM3B variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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