rs4465729
This variant is located in the RBKS gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
diverticular disease
Wu Y et al. “150 risk variants for diverticular disease of intestine prioritize cell types and enable polygenic prediction of disease susceptibility.” Cell Genomics 3(7):100326 (2023)
Allele C
OR 0.04
p 3.0e-12
N 454,768
Large GWAS
European
About RBKS
This gene encodes a member of the carbohydrate kinase PfkB family. The encoded protein phosphorylates ribose to form ribose-5-phosphate in the presence of ATP and magnesium as a first step in ribose metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
View all RBKS variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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