rs448809

This is a intron variant variant in the MEF2C-AS2 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

occupational attainment

Ko H et al. “Genome-wide association study of occupational attainment as a proxy for cognitive reserve.” Brain : a Journal of Neurology 145(4):1436-1448 (2022)

Allele G

OR 0.06

p 2.0e-14

N 248,847

Large GWAS

European

creativity measurement

Kim H et al. “Genome-wide association analyses using machine learning-based phenotyping reveal genetic architecture of occupational creativity and overlap with psychiatric disorders.” Psychiatry Research 333:115753 (2024)

Allele G

OR 0.02

p 2.0e-13

N 241,736

Large GWAS

European

Li WD et al. “A genome-wide association study of occupational creativity and its relations with well-being and career success.” Communications Biology 7(1):1092 (2024)

Allele G

OR 0.02

p 4.0e-12

N 219,473

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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