rs45461499
This is a protein-altering variant in the CDC20 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
asparaginase-induced acute pancreatitis
Liu C et al. “Clinical and Genetic Risk Factors for Acute Pancreatitis in Patients With Acute Lymphoblastic Leukemia.” Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 34(18):2133-40 (2016)
Allele A
OR 4.60
p 4.0e-9
N 5,185
Large GWAS
multi-ancestry
About CDC20
CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. [provided by RefSeq, Jul 2008]
View all CDC20 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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