rs45613035

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Eczematoid dermatitis, allergic rhinitis

Johansson Å et al. “Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema.” Human Molecular Genetics 28(23):4022-4041 (2019)

Allele C

OR 1.09

p 6.0e-20

N 323,807

Major Consortium StudyLarge GWAS

European

asthma

Ferreira MAR et al. “Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.” American Journal of Human Genetics 104(4):665-684 (2019)

Allele C

OR 1.11

p 6.0e-19

N 341,215

Large GWAS

European

Olafsdottir TA et al. “Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis.” Nature Communications 11(1):393 (2020)

Allele C

OR 1.08

p 5.0e-14

N 771,388

Large GWAS

European

Zhu Z et al. “Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.” The European Respiratory Journal 54(6) (2019)

Allele C

OR 1.08

p 1.0e-12

N 394,283

Large GWAS

multi-ancestry

Jia G et al. “Discerning asthma endotypes through comorbidity mapping.” Nature Communications 13(1):6712 (2022)

Allele C

OR 1.09

p 7.0e-13

N 305,098

Large GWAS

multi-ancestry

allergic disease

Ferreira MAR et al. “Age-of-onset information helps identify 76 genetic variants associated with allergic disease.” Plos Genetics 16(6):e1008725 (2020)

Allele C

OR 0.05

p 7.0e-13

N 477,968

Large GWAS

European

allergic disease, age at onset

Ferreira MAR et al. “Age-of-onset information helps identify 76 genetic variants associated with allergic disease.” Plos Genetics 16(6):e1008725 (2020)

Allele C

OR 0.04

p 2.0e-8

N 117,130

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

rs45613035

GWAS Catalog Trait Associations (4)

Eczematoid dermatitis, allergic rhinitis

asthma

allergic disease

allergic disease, age at onset

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