rs4592416
This variant is located in the HSD17B12 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
sleep duration trait
Dashti HS et al. “Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates.” Nature Communications 10(1):1100 (2019)
Allele G
OR 0.80
p 2.0e-10
N 446,118
Large GWAS
European
About HSD17B12
This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. [provided by RefSeq, Oct 2011]
View all HSD17B12 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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