rs4613079
This variant is located in the CDYL2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
interleukin 10 measurement
▶Research that mentions this SNP (1)
▶Genome-wide associated loci influencing interleukin (IL)-10, IL-1Ra, and IL-6 levels in African AmericansAssociationN=707Fasil Tekola Ayele et al.(2012)· Immunogenetics
This genome-wide association study (GWAS) identified genetic variants influencing interleukin levels in African Americans. IL-10 levels showed genome-wide significant associations with 8 SNPs, most notably rs5743185 in PMS1 (p=2.30×10⁻¹⁰), with successful replication of rs17365948 in YWHAZ. IL-1Ra levels showed suggestive associations with SNPs in ASB3 and the IL-1 gene family, with replication of rs4251961. IL-6 levels showed genome-wide significant association with one variant near RP11-314E23.1 (p=8.63×10⁻⁹).
About CDYL2
Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
View all CDYL2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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