rs4638225
This is a intron variant variant in the SHTN1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
brain attribute
van der Meer D et al. “The genetic architecture of human cortical folding.” Science Advances 7(51):eabj9446 (2021)
Allele A
OR 22.59
p 6.0e-113
N 33,748
Large GWAS
European
About SHTN1
Enables identical protein binding activity. Involved in positive regulation of neuron migration. Located in cytoplasm and microtubule. [provided by Alliance of Genome Resources, Jul 2025]
View all SHTN1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…