rs4658046

GWAS Catalog Trait Associations (57)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

uroplakin-3b-like protein measurement

Pietzner M et al. Mapping the proteo-genomic convergence of human diseases. Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.34
p 2.0e-147
N 10,708
Large GWAS
European

interleukin-10 receptor subunit alpha measurement

Pietzner M et al. Mapping the proteo-genomic convergence of human diseases. Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.33
p 1.0e-137
N 10,708
Large GWAS
European

endothelin-converting enzyme 1 measurement

Pietzner M et al. Mapping the proteo-genomic convergence of human diseases. Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.33
p 1.0e-132
N 10,708
Large GWAS
European

age-related macular degeneration

Allele C
OR 1.38
p 3.0e-114
N 105,248
Meta-analysisLarge GWAS
European

cytochrome c oxidase assembly factor 3 homolog, mitochondrial measurement

Pietzner M et al. Mapping the proteo-genomic convergence of human diseases. Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.29
p 2.0e-101
N 10,708
Large GWAS
European

kelch-like protein 13 measurement

Pietzner M et al. Mapping the proteo-genomic convergence of human diseases. Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.26
p 3.0e-83
N 10,708
Large GWAS
European

retinoblastoma-associated protein measurement

Pietzner M et al. Mapping the proteo-genomic convergence of human diseases. Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.26
p 5.0e-78
N 10,708
Large GWAS
European

keratin, type II cytoskeletal 7 measurement

Pietzner M et al. Mapping the proteo-genomic convergence of human diseases. Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.25
p 1.0e-73
N 10,708
Large GWAS
European

cadherin-related family member 5 measurement

Pietzner M et al. Mapping the proteo-genomic convergence of human diseases. Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.24
p 6.0e-69
N 10,708
Large GWAS
European

leucine-rich repeat transmembrane neuronal protein 4 measurement

Pietzner M et al. Mapping the proteo-genomic convergence of human diseases. Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.24
p 4.0e-67
N 10,708
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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