rs4662330

This is a regulatory region variant variant in the ARHGAP15 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

coronary artery disease

Aragam KG et al. “Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants.” Nature Genetics 54(12):1803-1815 (2022)

Allele T

OR 1.05

p 7.0e-12

N 1,165,690

Large GWAS

European, NR

About ARHGAP15

RHO GTPases (see ARHA; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003 [PubMed 12650940]).[supplied by OMIM, Mar 2008]

View all ARHGAP15 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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