rs4662344
This variant is located in the ARHGAP15 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
diverticular disease
Sigurdsson S et al. “Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis.” Nature Communications 8:15789 (2017)
Allele T
OR 1.23
p 2.0e-18
N 251,377
Large GWAS
European
diverticulitis
Sigurdsson S et al. “Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis.” Nature Communications 8:15789 (2017)
Allele T
OR 1.26
p 5.0e-9
N 248,715
Large GWAS
European
About ARHGAP15
RHO GTPases (see ARHA; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003 [PubMed 12650940]).[supplied by OMIM, Mar 2008]
View all ARHGAP15 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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