rs4677813

This is a upstream gene variant variant in the XXYLT1 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body weight

Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)

Allele C

OR 0.01

p 2.0e-10

N 525,535

Large GWAS

multi-ancestry

body height

Richardson TG et al. “Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study.” Bmj (clinical Research Ed.) 369:m1203 (2020)

Allele T

OR 0.01

p 2.0e-8

N 453,169

Large GWAS

European

About XXYLT1

Enables magnesium ion binding activity; manganese ion binding activity; and xylosyl alpha-1,3-xylosyltransferase activity. Involved in O-glycan processing. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2025]

View all XXYLT1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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