rs4687625
This is a upstream gene variant variant in the NT5DC2 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
intelligence
Savage JE et al. “Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.” Nature Genetics 50(7):912-919 (2018)
Allele T
OR 7.04
p 2.0e-12
N 269,867
Meta-analysisLarge GWAS
European
memory performance
Lahti J et al. “Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.” Molecular Psychiatry 27(11):4419-4431 (2022)
Allele T
OR 6.29
p 3.0e-10
N 28,909
Large GWAS
European
About NT5DC2
Predicted to enable 5'-nucleotidase activity. Predicted to be involved in negative regulation of dopamine biosynthetic process; negative regulation of oxidoreductase activity; and negative regulation of peptidyl-serine phosphorylation. Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
View all NT5DC2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…