rs4705962
This is a 3 prime utr variant variant in the KIF3A gene.
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
atopic eczema
Paternoster L et al. “Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.” Nature Genetics 47(12):1449-1456 (2015)
Allele T
OR 1.10
p 7.0e-12
N 116,863
Large GWAS
multi-ancestry
allergic disease
Ferreira MAR et al. “Age-of-onset information helps identify 76 genetic variants associated with allergic disease.” Plos Genetics 16(6):e1008725 (2020)
Allele T
OR 0.03
p 2.0e-10
N 477,968
Large GWAS
European
allergic disease, age at onset
Ferreira MAR et al. “Age-of-onset information helps identify 76 genetic variants associated with allergic disease.” Plos Genetics 16(6):e1008725 (2020)
Allele T
OR 0.03
p 2.0e-10
N 117,130
Large GWAS
European
asthma
Pividori M et al. “Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.” The Lancet. Respiratory Medicine 7(6):509-522 (2019)
Allele T
OR 0.98
p 6.0e-10
N 37,846
Large GWAS
European
About KIF3A
Enables protein phosphatase binding activity; small GTPase binding activity; and spectrin binding activity. Involved in protein localization to cell junction and protein transport. Located in centriole; centrosome; and spindle microtubule. Part of kinesin II complex. Biomarker of silicosis. [provided by Alliance of Genome Resources, Jul 2025]
View all KIF3A variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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