rs4719648

This is a regulatory region variant variant in the AMZ1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

birth weight

Warrington NM et al. “Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.” Nature Genetics 51(5):804-814 (2019)

Allele C

OR 0.02

p 3.0e-13

N 321,223

Large GWAS

multi-ancestry

About AMZ1

Predicted to enable metal ion binding activity and metallopeptidase activity. Predicted to be involved in proteolysis. [provided by Alliance of Genome Resources, Jul 2025]

View all AMZ1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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